Rambabu  G.
rgundla@gitam.edu

Rambabu G.

Professor

Education
Ph. D.
Institute
GITAM School of Technology - Visakhapatnam
Department
Biotechnology
Research Areas
  • Medicinal Chemistry
  • Computational Chemistry
  • Material Science
  • Analytical Chemistry
rgundla@gitam.edu

Synthesis of New Chiral (R)BINOL Derivatives under Microwave Irradiation andEvaluation of their Antibacterial and Glucosidase Inhibitory ActivityChemistry select, Google scholar, -2019, accepted, 00

Rational design, molecular docking and synthesis of novel homopiperazinelinked imidazo[1,2a]pyrimidine derivatives as potent cytotoxic andantimicrobial agentsBioorganic & Medicinal Chemistry Letters, Scopus, -2019, 0, 00

Synthesis, Characterization and Antibacterial Activity of Some NovelC7Substituted2morpholinoN(pyridin2ylmethyl)quinazolin4amine DerivativesDer Pharma Chemica, , Others, -2018, 10, 40-48

Design, Synthesis and Biological Evaluation of 2(((5aryl1,2,4oxadiazol3yl)methyl)thio)benzo[d]oxazolesNew Antiinflammatory and Antioxidant AgentsChemistry select, Scopus, -2018, 3, 1-7

Focused library design and synthesis of 2mercapto benzothiazolelinked 1,2,4oxadiazoles as COX25LOX inhibitorsJournal of Molecular Structure , Scopus, -2018, 1159, 193-204

Synthesis and biological potentials of some new 1,3,4oxadiazoleanaloguesMedicinal chemistry research , Scopus, -2018, 27, 864-883

Stabilityindicating method ofentacaponerelated substances usingUPLC in finished dosage formCURRENT SCIENCE, Scopus, -2018, 114, 644

Synthesis, Biological Evaluation and Docking Studies of 1,3,4OxadiazoleFused Benzothiazole Derivatives for Anticancer DrugsLetters in Drug Design & Discovery, Scopus, -2018, 15, 199-1307

An approach towards the oxidation of 2amino4Hchromenes to 2imino2HchromenesTetrahedron Letters , Scopus, -2018, 59, 4616-4619

Molecular hybrid design, synthesis and biological evaluation of Nphenyl sulfonamide linked Nacyl hydrazone derivatives functioning as COX2 inhibitors new antiinflammatory, antioxidant and antibacterial agentsNEW JOURNAL OF CHEMISTRY, Scopus, -2017, 41, 13516-13532

New AntiInflammatory Hybrid NAcyl HydrazoneLinked Isoxazole Derivatives as COX2 InhibitorsRational Design, Synthesis and Biological Evaluation Chemistry selective, Scopus, -2017, 2, 8091-8100

A diversity oriented synthesis of natural product inspired molecular librariesOrganic & Biomolecular Chemistry, Scopus, -2017, 15, 9108-9120

Synthesis, molecular docking and in vitroantiproliferative activity of novel pyrano[3,2c]carbazole derivativesNew J. Chem.,, Scopus, -2016, 40, 8305--8315

DESIGNING NOVEL MEK1 INHIBITORS AS ANTICANCER AGENTSIJLP, Google scholar, -2016, 6, 22-33

Ionic liquidwater mixture promoted organictransformationsRSC Adv., , 5, , Scopus, -2015, 5, 51035-51054

Design, synthesis, and biological evaluation of quinazolinederivatives as aglucosidase inhibitorsMedicinal chemistry research , Scopus, -2015, 24, 2227-2237

Boronic acidcontaining CXCR12 antagonists optimization ofmetabolic stability, in vivo evaluation, and a proposed receptorbinding modelBMCL, Web of science, -2015, 25, 2280-2284

Design, synthesis and screening studies of potent thiazol2amine derivatives as fibroblast growth factor receptor 1 inhibitors. Current Topics in Medicinal Chemistry, Web of science, -2014, 14, 2031-2041

Pyrrolidine and piperidine based chiral spiro andfused scaffolds via buildcouplepair approach. RSC Adv, Scopus, -2014, 14, 10619-10626

A reagent based DOS strategy via Evans chiral auxiliaryhighly stereoselective Michael reaction towardsoptically active quinolizidinones, piperidinones andpyrrolidinones3RSC Adv., Scopus, -2013, 3, 2404-2411

Diversity Oriented Synthesis of Macrocyclic Diaryl Ethers by DtzBenzannulationAsian J. Org. Chem, Web of science, -2013, 2, 862-868

Synthesis of Privileged Scaffolds by Using DiversityOriented SynthesisChem. Asian J. 2013, 00, 0 0, Web of science, -2013, 0, 00

Fibroblast Growth Factor Receptor InhibitorsCurrent Pharmaceutical Design, Web of science, -2013, 19, 687-701

Development of glucosidase inhibitors by roomtemperature CC cross couplings of quinazolinonesOrg. Biomol. Chem, Scopus, -2013, 11, 4778-4791

ReagentBased DOS Developing a Diastereoselective Methodology toAccess Spirocyclic and Fused Heterocyclic Ring Systems**Chem. Asian J., Web of science, -2012, 7, 2351-2360

Molecular modeling of Bt Cry1Ac (DIDII)ASAL (Allium sativum lectin)fusionprotein and its interaction with aminopeptidase N (APN) receptor ofManduca sextaJournal of Molecular Graphics and Modelling , Scopus, -2012, 33, 61-67

Discovery and Preclinical Evaluation of a Novel Class of Cytotoxic Propynoic Acid Carbamoyl Methyl Amides (PACMAs)J. Med. Chem., Scopus, -2011, 54, 2902-2914

Virtual screening studies on HIV1 reverse transcriptase inhibitorsto design potent leadsEuropean Journal of Medicinal Chemistry, Scopus, -2011, 46, 851-859

A wideranging review on Nasicon type materialsJ Mater Sci, Scopus, -2011, 46, 2821-2837

A threedimensional pharmacophoremodelling of ITK inhibitors and virtualscreening for novel inhibitorsSAR and QSAR in Environmental Research, Scopus, -2011, 22, 171-190

Ligandbased and structurebased approaches in identifyingideal pharmacophore against cJun Nterminal kinase3J Mol Model, Scopus, -2011, 17, 151-163

Insilico studies on anthrax lethal factor inhibitors Pharmacophore modeling andvirtual screening approaches towards designing of novel inhibitors for a killerJournal of Molecular Graphics and Modelling , Scopus, -2010, 29 , 256-265

Three Dimensional Molecular Field Analysis of Thiomorpholine Analogs of TACE Inhibitors Using Receptor Based AlignmentLetters in Drug Design & Discovery, Web of science, -2010, 7 , 269-274

Combined pharmacophore and structureguided studies to identify diverseHSP90 inhibitorsJournal of Molecular Graphics and Modelling, Scopus, -2010, 28, 472-477

Modeling of human caspase5 protein and docking studies of caspase5 inhibitors against modeled caspase5Journal of Global Pharma Technology , Google scholar, -2010, 2, 1-5

Discovery of potential ZAP70 kinase inhibitors Pharmacophore design,database screening and docking studiesEuropean Journal of Medicinal Chemistry, Scopus, -2009, 44, 4793-4800

Knowledge basedidentification of MAOB selective inhibitors using pharmacophore and structure based virtual screening modelsEuropean Journal of Medicinal Chemistry, Scopus, -2009, 44, 3584-3590

Discovery of Novel SmallMolecule Inhibitors of Human Epidermal Growth Factor Receptor2Combined Ligand and TargetBased ApproachJ. Med. Chem. , Scopus, -2008, 51, 3367-3377

Discovery of 3acetyl4hydroxy2pyranone derivatives and theirdifluoridoborate complexes as a novel class of HIV1 integrase InhibitorsBioorganic & Medicinal Chemistry, Scopus, -2008, 16, 8988-8998

QSAR analysis of 1,3diaryl4,5,6,7tetrahydro2Hisoindolederivatives as selective COX2 inhibitorsEuropean Journal of Medicinal Chemistry , Scopus, -2008, 43, 1559-1569

Powder Xray diffraction, infrared and conductivity studiesof AgSbMP3O12 (M Al, Ga, Fe and Cr)Materials Research Bulletin , Scopus, -2008, 43, 1509-1518

Pharmacophore modeling and virtual screening studies to designsome potential histone deacetylase inhibitors as new leadsJournal of Molecular Graphics and Modelling , Scopus, -2008, 26, 935-946

HIV1 Integrase Inhibitors2005^2006 UpdateMedicinal Research Reviews, Scopus, -2008, 28, 118-154

Preparation, characterization and conductivity studiesof a Nasicon system Ag32xTaxAl2x (PO4)3.(a) 204, No. phys. stat. sol. , Web of science, -2007, 10, 3454-3462

Preparation, characterization, conductivity and thermalexpansion studies of Ca0.5SbMP3O12 (M Al, Fe, Cr)J Mater Sci, Web of science, -2007, 42, 3613-3620

Pharmacophore mapping of diverse classesof farnesyltransferase inhibitors. Bioorganic & Medicinal Chemistry Letters, Scopus, -2007, 17, 1594-1600

Preparation, characterization, and impedance studies of Li Sb M ( P O 4 ) 3 ( M Al , Fe,and Cr) JOURNAL OF APPLIED PHYSICS, Web of science, -2006, 100, 083707

Ligand Coordinate Analysis of SC558 from the Active Site to the Surface of COX2 AMolecular Dynamics Study. J. Chem. Inf. Model., Scopus, -2006, 46, 1784-1794

Synthesis, molecular docking, antiproliferative, and antimicrobialactivity of novel pyrano[3,2c]carbazole derivativesMed Chem Res, Scopus, -2006, 25, 2093-2103

A REVIEW ON ANTIHCV AGENTS TARGETING ACTIVE SITE AND ALLOSTERIC SITES OF NONSTRUCTURALPROTEIN 5B [NS5B]International Journal of Pharmacy and Pharmaceutical Sciences, Google scholar, -2006, 8, 1-18

Preparation, characterization and impedance study of AgTaMP3O12(MAl, Ga, In, Cr, Fe and Y)Solid State Ionics, Web of science, -2005, 176, 2701-2710

Virtual Screening of 4Anilinoquinazoline Analogues as EGFR Kinase InhibitorsImportance of Hydrogen Bonds in the Evaluation of Poses and Scoring FunctionsJ. Chem. Inf. Model, Web of science, -2005, 45, 725-738

Design of EGFR Kinase Inhibitors A LigandBased Approachand Its Confirmation with StructureBased StudiesBioorganic & Medicinal Chemistry , Scopus, -2003, 11, 4643-4653

Analogue Based Design of MMP13 (Collagenase3) Inhibitors. Bioorganic & Medicinal Chemistry Letters, Scopus, -2002, 12, 2689-2693

Title of the project Funded by Duration Sanctioned date
NHeterocyclic CarbeneStabilized Silaallenes, Silacumulenes, Phosphaallenes and Phosphacumulenes. DST 36 26-Oct-2017
Traditional and New Approaches Towards the Discovery of Dengue Protease Inhibitors Potent and Druglike Antiviral Agents against Dengue Fever SERB_DST 36 04-Jun-2016
Title of the project Funded by Duration Sanctioned date
Title of the book Book / Chapter Name of the publisher Subject area Edition Page numbers ISBN Published year
ComputerAided Techniques in Design of HIV1 Integrase Inhibitors Chapters Wiley Series Medicinal Chemistry 10 389-413 9780470184745 2011
Board name Journal name
Board name Journal name
Wiley Chemistry Select
Elsevier Journal Molecular Structure
Seminar name Organized by Venue Start date End date Title of the paper presented Role Co presenter
National Nalanda college of pharmacy, Nalgonda Nalgonda 29-Mar-2019 29-Mar-2019 Resource Person
National GITAM, Hyederabd hyderabad 06-Sep-2018 08-Sep-2018 Organized
National GITAM Hyderabad 23-Oct-2017 23-Oct-2017 Organized
National hyderabad hyderabad 14-Jul-2017 16-Jul-2017 Resource Person
National Tara Govt. College ,Sangareddy Tara Govt. College ,Sangareddy 29-Dec-2016 30-Dec-2016 Resource Person
National GITAM GITAM, Hyderabad 02-Apr-2016 02-Apr-2016 Organized
National SKSD mahila college, Tanuku Tanuku 30-Jan-2016 31-Jan-2016 Resource Person
National Tara Govt. College ,Sangareddy Tara Govt. College ,Sangareddy 08-Jan-2015 09-Jan-2015 Resource Person
Seminar name Organized by Venue Start date End date Title of the paper presented Role Co presenter
International MGU, KOTTAYAM, KERALA KOTTAYAM, KERALA 08-Dec-2017 10-Dec-2017 Resource Person
International jnu jnu,delhi 07-Apr-2017 09-Apr-2017 Resource Person
International jntuh jntuh 04-Oct-2016 06-Oct-2016 Participated
International Schrodinger IISc, Bengolore 16-Sep-2013 17-Sep-2013 Resource Person
International GITAM GITAM, Vishakapatnam 28-Jul-2011 29-Jul-2011 Participated
International OMICS Hyderabad 21-Mar-2011 23-Mar-2011 Resource Person
Title of the thesis Name of the student Name of the college / university Major subject area Year of admission Type of admission Thesis specification
Rational Design, Synthesis of hetero cyclic compouds of anti cancer agents Madhu Sudhana Reddy Gangireddy GITAM Medicinal Chemistry 2015 Part time PhD
Novel Design, Synthesis of hetero cyclic compouds of anti cancer agents Manohar Mantipally GITAM Medicinal Chemistry 2015 Part time PhD
Design, Synthesis of hetero cyclic compouds of anti viral agents Venkatnarayana chowdary Maddipati GITAM Medicinal Chemistry 2015 Part time PhD
Design, Synthesis of hetero cyclic compouds of anti cancer agents Gopal Muddasani GITAM Medicinal Chemistry 2015 Part time PhD
Novel Design, Synthesis of hetero cyclic compouds of anti cancer agents Kalisavali GITAM Medicinal Chemistry 2015 Part time PhD
Design, Synthesis of hetero cyclic compouds of anti viral agents Sidvilas GITAM Medicinal Chemistry 2015 Part time PhD
Design, Synthesis of hetero cyclic compouds of anti cancer agents Anil Kumar GITAM Medicinal Chemistry 2015 Part time PhD
Design, synthesis and insilco studies of BenzothiazoleBenzooxazole based hetrero cyclic agents as a COX2 inhibitors Satyanarayan.Y GITAM Medicinal Chemistry 2014 Part time PhD
Identification, synthesis and biological evaluation of new Quinazoline and BINOL based Antidiabetic and Antibacterial agents Ashok Reddy.A GITAM Medicinal Chemistry 2014 Part time PhD
Title of the thesis Name of the student Name of the college / university Major subject area Year of admission Type of admission Thesis specification
DEVELOPMENT AND VALIDATION OF NOVEL STABILITY INDICATING METHODS FOR SELECTED DRUGS OF CANCER AND PARKINSON DISEASES USING RPHPLC AND UPLC TECHNIQUES Naresh Konduru GITAM Analytical Chemistry 2018 Part time PhD
Title of the thesis Name of the student Name of the college / university Major subject area Year of admission Type of admission Thesis specification
Name of the award Awarded by Awarded year
Best Researcher GITAM 2017
Best Employee GVKBIO 2012
Organization name Membership category Membership type
Indian Science Congress Association Life Member
Title Application number Category Submitted date
Title Application number Category Submitted date
Title Application number Category Submitted date
Pesticidal Compositions And Processes Related Thereto US 9,615,576 B2 US 17 Feb, 2017
Pesticidal Compositions And Processes Related Thereto US 20140206537A1 US 25 Mar, 2014
Pesticidal Compositions And Processes Related Thereto US 9,615,576 B2 US 21 Jun, 2012