Rambabu Gundla

Rambabu Gundla

Professor, Chemistry, GSS, HYD

Education
Ph. D.
Email ID
rgundla@gitam.edu
Education
Ph. D.
Research Areas
  • Medicinal Chemistry
  • Computational Chemistry
  • Material Science
  • Analytical Chemistry

Education

Degree NameInstitute & College nameYear of Graduation/Award
ChemistryOsmania University2006
MSCMSC Chemistry1999
B.ScSRBGNR1996

Experience

DesignationOrganizationFrom DateTo Date
GVKBIO - Biocampus-Faculty inchargeGVKBIO01-07-200830-07-2014
Principal ScientistGVKBIO01-07-200830-07-2014
Post doc - RAPDF03-01-200707-05-2008
Sr.ScientistGVKBIO02-05-200120-12-2006
GVKBIO - Biocampus-FacultyGVKBIO02-05-200120-12-2006

Awards

Award nameAward OrganizationAwarded year
Best researcher of GITAM HydGITAM University2017
Best Research ScientistGVKBIO2013

Synthesis of New Chiral (R)BINOL Derivatives under Microwave Irradiation andEvaluation of their Antibacterial and Glucosidase Inhibitory ActivityChemistry select, Google scholar, -2019, accepted, 00

Rational design, molecular docking and synthesis of novel homopiperazinelinked imidazo[1,2a]pyrimidine derivatives as potent cytotoxic andantimicrobial agentsBioorganic & Medicinal Chemistry Letters, Scopus, -2019, 0, 00

Synthesis, Characterization and Antibacterial Activity of Some NovelC7Substituted2morpholinoN(pyridin2ylmethyl)quinazolin4amine DerivativesDer Pharma Chemica, , Others, -2018, 10, 40-48

Design, Synthesis and Biological Evaluation of 2(((5aryl1,2,4oxadiazol3yl)methyl)thio)benzo[d]oxazolesNew Antiinflammatory and Antioxidant AgentsChemistry select, Scopus, -2018, 3, 1-7

Focused library design and synthesis of 2mercapto benzothiazolelinked 1,2,4oxadiazoles as COX25LOX inhibitorsJournal of Molecular Structure , Scopus, -2018, 1159, 193-204

Synthesis and biological potentials of some new 1,3,4oxadiazoleanaloguesMedicinal chemistry research , Scopus, -2018, 27, 864-883

Stabilityindicating method ofentacaponerelated substances usingUPLC in finished dosage formCURRENT SCIENCE, Scopus, -2018, 114, 644

Synthesis, Biological Evaluation and Docking Studies of 1,3,4OxadiazoleFused Benzothiazole Derivatives for Anticancer DrugsLetters in Drug Design & Discovery, Scopus, -2018, 15, 199-1307

An approach towards the oxidation of 2amino4Hchromenes to 2imino2HchromenesTetrahedron Letters , Scopus, -2018, 59, 4616-4619

Molecular hybrid design, synthesis and biological evaluation of Nphenyl sulfonamide linked Nacyl hydrazone derivatives functioning as COX2 inhibitors new antiinflammatory, antioxidant and antibacterial agentsNEW JOURNAL OF CHEMISTRY, Scopus, -2017, 41, 13516-13532

New AntiInflammatory Hybrid NAcyl HydrazoneLinked Isoxazole Derivatives as COX2 InhibitorsRational Design, Synthesis and Biological Evaluation Chemistry selective, Scopus, -2017, 2, 8091-8100

A diversity oriented synthesis of natural product inspired molecular librariesOrganic & Biomolecular Chemistry, Scopus, -2017, 15, 9108-9120

Synthesis, molecular docking and in vitroantiproliferative activity of novel pyrano[3,2c]carbazole derivativesNew J. Chem.,, Scopus, -2016, 40, 8305--8315

DESIGNING NOVEL MEK1 INHIBITORS AS ANTICANCER AGENTSIJLP, Google scholar, -2016, 6, 22-33

Ionic liquidwater mixture promoted organictransformationsRSC Adv., , 5, , Scopus, -2015, 5, 51035-51054

Design, synthesis, and biological evaluation of quinazolinederivatives as aglucosidase inhibitorsMedicinal chemistry research , Scopus, -2015, 24, 2227-2237

Boronic acidcontaining CXCR12 antagonists optimization ofmetabolic stability, in vivo evaluation, and a proposed receptorbinding modelBMCL, Web of science, -2015, 25, 2280-2284

Design, synthesis and screening studies of potent thiazol2amine derivatives as fibroblast growth factor receptor 1 inhibitors. Current Topics in Medicinal Chemistry, Web of science, -2014, 14, 2031-2041

Pyrrolidine and piperidine based chiral spiro andfused scaffolds via buildcouplepair approach. RSC Adv, Scopus, -2014, 14, 10619-10626

A reagent based DOS strategy via Evans chiral auxiliaryhighly stereoselective Michael reaction towardsoptically active quinolizidinones, piperidinones andpyrrolidinones3RSC Adv., Scopus, -2013, 3, 2404-2411

Diversity Oriented Synthesis of Macrocyclic Diaryl Ethers by DtzBenzannulationAsian J. Org. Chem, Web of science, -2013, 2, 862-868

Synthesis of Privileged Scaffolds by Using DiversityOriented SynthesisChem. Asian J. 2013, 00, 0 0, Web of science, -2013, 0, 00

Fibroblast Growth Factor Receptor InhibitorsCurrent Pharmaceutical Design, Web of science, -2013, 19, 687-701

Development of glucosidase inhibitors by roomtemperature CC cross couplings of quinazolinonesOrg. Biomol. Chem, Scopus, -2013, 11, 4778-4791

ReagentBased DOS Developing a Diastereoselective Methodology toAccess Spirocyclic and Fused Heterocyclic Ring Systems**Chem. Asian J., Web of science, -2012, 7, 2351-2360

Molecular modeling of Bt Cry1Ac (DIDII)ASAL (Allium sativum lectin)fusionprotein and its interaction with aminopeptidase N (APN) receptor ofManduca sextaJournal of Molecular Graphics and Modelling , Scopus, -2012, 33, 61-67

Discovery and Preclinical Evaluation of a Novel Class of Cytotoxic Propynoic Acid Carbamoyl Methyl Amides (PACMAs)J. Med. Chem., Scopus, -2011, 54, 2902-2914

Virtual screening studies on HIV1 reverse transcriptase inhibitorsto design potent leadsEuropean Journal of Medicinal Chemistry, Scopus, -2011, 46, 851-859

A wideranging review on Nasicon type materialsJ Mater Sci, Scopus, -2011, 46, 2821-2837

A threedimensional pharmacophoremodelling of ITK inhibitors and virtualscreening for novel inhibitorsSAR and QSAR in Environmental Research, Scopus, -2011, 22, 171-190

Ligandbased and structurebased approaches in identifyingideal pharmacophore against cJun Nterminal kinase3J Mol Model, Scopus, -2011, 17, 151-163

Insilico studies on anthrax lethal factor inhibitors Pharmacophore modeling andvirtual screening approaches towards designing of novel inhibitors for a killerJournal of Molecular Graphics and Modelling , Scopus, -2010, 29 , 256-265

Three Dimensional Molecular Field Analysis of Thiomorpholine Analogs of TACE Inhibitors Using Receptor Based AlignmentLetters in Drug Design & Discovery, Web of science, -2010, 7 , 269-274

Combined pharmacophore and structureguided studies to identify diverseHSP90 inhibitorsJournal of Molecular Graphics and Modelling, Scopus, -2010, 28, 472-477

Modeling of human caspase5 protein and docking studies of caspase5 inhibitors against modeled caspase5Journal of Global Pharma Technology , Google scholar, -2010, 2, 1-5

Discovery of potential ZAP70 kinase inhibitors Pharmacophore design,database screening and docking studiesEuropean Journal of Medicinal Chemistry, Scopus, -2009, 44, 4793-4800

Knowledge basedidentification of MAOB selective inhibitors using pharmacophore and structure based virtual screening modelsEuropean Journal of Medicinal Chemistry, Scopus, -2009, 44, 3584-3590

Discovery of Novel SmallMolecule Inhibitors of Human Epidermal Growth Factor Receptor2Combined Ligand and TargetBased ApproachJ. Med. Chem. , Scopus, -2008, 51, 3367-3377

Discovery of 3acetyl4hydroxy2pyranone derivatives and theirdifluoridoborate complexes as a novel class of HIV1 integrase InhibitorsBioorganic & Medicinal Chemistry, Scopus, -2008, 16, 8988-8998

QSAR analysis of 1,3diaryl4,5,6,7tetrahydro2Hisoindolederivatives as selective COX2 inhibitorsEuropean Journal of Medicinal Chemistry , Scopus, -2008, 43, 1559-1569

Powder Xray diffraction, infrared and conductivity studiesof AgSbMP3O12 (M Al, Ga, Fe and Cr)Materials Research Bulletin , Scopus, -2008, 43, 1509-1518

Pharmacophore modeling and virtual screening studies to designsome potential histone deacetylase inhibitors as new leadsJournal of Molecular Graphics and Modelling , Scopus, -2008, 26, 935-946

HIV1 Integrase Inhibitors2005^2006 UpdateMedicinal Research Reviews, Scopus, -2008, 28, 118-154

Preparation, characterization and conductivity studiesof a Nasicon system Ag32xTaxAl2x (PO4)3.(a) 204, No. phys. stat. sol. , Web of science, -2007, 10, 3454-3462

Preparation, characterization, conductivity and thermalexpansion studies of Ca0.5SbMP3O12 (M Al, Fe, Cr)J Mater Sci, Web of science, -2007, 42, 3613-3620

Pharmacophore mapping of diverse classesof farnesyltransferase inhibitors. Bioorganic & Medicinal Chemistry Letters, Scopus, -2007, 17, 1594-1600

Preparation, characterization, and impedance studies of Li Sb M ( P O 4 ) 3 ( M Al , Fe,and Cr) JOURNAL OF APPLIED PHYSICS, Web of science, -2006, 100, 083707

Ligand Coordinate Analysis of SC558 from the Active Site to the Surface of COX2 AMolecular Dynamics Study. J. Chem. Inf. Model., Scopus, -2006, 46, 1784-1794

Synthesis, molecular docking, antiproliferative, and antimicrobialactivity of novel pyrano[3,2c]carbazole derivativesMed Chem Res, Scopus, -2006, 25, 2093-2103

A REVIEW ON ANTIHCV AGENTS TARGETING ACTIVE SITE AND ALLOSTERIC SITES OF NONSTRUCTURALPROTEIN 5B [NS5B]International Journal of Pharmacy and Pharmaceutical Sciences, Google scholar, -2006, 8, 1-18

Preparation, characterization and impedance study of AgTaMP3O12(MAl, Ga, In, Cr, Fe and Y)Solid State Ionics, Web of science, -2005, 176, 2701-2710

Virtual Screening of 4Anilinoquinazoline Analogues as EGFR Kinase InhibitorsImportance of Hydrogen Bonds in the Evaluation of Poses and Scoring FunctionsJ. Chem. Inf. Model, Web of science, -2005, 45, 725-738

Design of EGFR Kinase Inhibitors A LigandBased Approachand Its Confirmation with StructureBased StudiesBioorganic & Medicinal Chemistry , Scopus, -2003, 11, 4643-4653

Analogue Based Design of MMP13 (Collagenase3) Inhibitors. Bioorganic & Medicinal Chemistry Letters, Scopus, -2002, 12, 2689-2693

Title of the projectFunded byDurationSanctioned date
NHeterocyclic CarbeneStabilized Silaallenes, Silacumulenes, Phosphaallenes and Phosphacumulenes.DST3626-Oct-2017
Traditional and New Approaches Towards the Discovery of Dengue Protease Inhibitors Potent and Druglike Antiviral Agents against Dengue FeverSERB_DST3604-Jun-2016
Title of the projectFunded byDurationSanctioned date
Title of the bookBook / ChapterName of the publisherSubject areaEditionPage numbersISBNPublished year
ComputerAided Techniques in Design of HIV1 Integrase InhibitorsChaptersWiley SeriesMedicinal Chemistry10389-41397804701847452011
Board nameJournal name
Board nameJournal name
WileyChemistry Select
ElsevierJournal Molecular Structure
Seminar nameOrganized byVenueStart dateEnd dateTitle of the paper presentedRoleCo presenter
NationalNalanda college of pharmacy, NalgondaNalgonda29-Mar-201929-Mar-2019Resource Person
NationalGITAM, Hyederabdhyderabad06-Sep-201808-Sep-2018Organized
NationalGITAMHyderabad23-Oct-201723-Oct-2017Organized
Nationalhyderabadhyderabad14-Jul-201716-Jul-2017Resource Person
NationalTara Govt. College ,SangareddyTara Govt. College ,Sangareddy29-Dec-201630-Dec-2016Resource Person
NationalGITAMGITAM, Hyderabad02-Apr-201602-Apr-2016Organized
NationalSKSD mahila college, TanukuTanuku30-Jan-201631-Jan-2016Resource Person
NationalTara Govt. College ,SangareddyTara Govt. College ,Sangareddy08-Jan-201509-Jan-2015Resource Person
Seminar nameOrganized byVenueStart dateEnd dateTitle of the paper presentedRoleCo presenter
InternationalMGU, KOTTAYAM, KERALAKOTTAYAM, KERALA08-Dec-201710-Dec-2017Resource Person
Internationaljnujnu,delhi07-Apr-201709-Apr-2017Resource Person
Internationaljntuhjntuh04-Oct-201606-Oct-2016Participated
InternationalSchrodingerIISc, Bengolore16-Sep-201317-Sep-2013Resource Person
InternationalGITAMGITAM, Vishakapatnam28-Jul-201129-Jul-2011Participated
InternationalOMICSHyderabad21-Mar-201123-Mar-2011Resource Person
Title of the thesisName of the studentName of the college / universityMajor subject areaYear of admissionType of admissionThesis specification
Rational Design, Synthesis of hetero cyclic compouds of anti cancer agentsMadhu Sudhana Reddy GangireddyGITAMMedicinal Chemistry2015Part timePhD
Novel Design, Synthesis of hetero cyclic compouds of anti cancer agentsManohar MantipallyGITAMMedicinal Chemistry2015Part timePhD
Design, Synthesis of hetero cyclic compouds of anti viral agentsVenkatnarayana chowdary MaddipatiGITAMMedicinal Chemistry2015Part timePhD
Design, Synthesis of hetero cyclic compouds of anti cancer agentsGopal MuddasaniGITAMMedicinal Chemistry2015Part timePhD
Novel Design, Synthesis of hetero cyclic compouds of anti cancer agentsKalisavaliGITAMMedicinal Chemistry2015Part timePhD
Design, Synthesis of hetero cyclic compouds of anti viral agentsSidvilasGITAMMedicinal Chemistry2015Part timePhD
Design, Synthesis of hetero cyclic compouds of anti cancer agentsAnil KumarGITAMMedicinal Chemistry2015Part timePhD
Design, synthesis and insilco studies of BenzothiazoleBenzooxazole based hetrero cyclic agents as a COX2 inhibitorsSatyanarayan.YGITAMMedicinal Chemistry2014Part timePhD
Identification, synthesis and biological evaluation of new Quinazoline and BINOL based Antidiabetic and Antibacterial agentsAshok Reddy.AGITAMMedicinal Chemistry2014Part timePhD
Title of the thesisName of the studentName of the college / universityMajor subject areaYear of admissionType of admissionThesis specification
DEVELOPMENT AND VALIDATION OF NOVEL STABILITY INDICATING METHODS FOR SELECTED DRUGS OF CANCER AND PARKINSON DISEASES USING RPHPLC AND UPLC TECHNIQUESNaresh KonduruGITAMAnalytical Chemistry2018Part timePhD
Title of the thesisName of the studentName of the college / universityMajor subject areaYear of admissionType of admissionThesis specification
Name of the awardAwarded byAwarded year
Best ResearcherGITAM2017
Best EmployeeGVKBIO2012
Organization nameMembership categoryMembership type
Indian Science Congress AssociationLifeMember
TitleApplication numberCategorySubmitted date
TitleApplication numberCategorySubmitted date
TitleApplication numberCategorySubmitted date
Pesticidal Compositions And Processes Related TheretoUS 9,615,576 B2US17 Feb, 2017
Pesticidal Compositions And Processes Related TheretoUS 20140206537A1US25 Mar, 2014
Pesticidal Compositions And Processes Related TheretoUS 9,615,576 B2US21 Jun, 2012