
Rambabu G.
Professor, Chemistry, GSS, HYD
Education
Ph. D.Email ID
Education
Ph. D.Research Areas
- Medicinal Chemistry
- Computational Chemistry
- Material Science
- Analytical Chemistry
Education
Degree Name | Institute & College name | Year of Graduation/Award |
---|---|---|
Chemistry | Osmania University | 2006 |
MSC | MSC Chemistry | 1999 |
B.Sc | SRBGNR | 1996 |
Experience
Designation | Organization | From Date | To Date |
---|---|---|---|
GVKBIO - Biocampus-Faculty incharge | GVKBIO | 01-07-2008 | 30-07-2014 |
Principal Scientist | GVKBIO | 01-07-2008 | 30-07-2014 |
Post doc - RA | 03-01-2007 | 07-05-2008 | |
Sr.Scientist | GVKBIO | 02-05-2001 | 20-12-2006 |
GVKBIO - Biocampus-Faculty | GVKBIO | 02-05-2001 | 20-12-2006 |
Awards
Award name | Award Organization | Awarded year |
---|---|---|
Best researcher of GITAM Hyd | GITAM University | 2017 |
Best Research Scientist | GVKBIO | 2013 |
Synthesis of New Chiral (R)BINOL Derivatives under Microwave Irradiation andEvaluation of their Antibacterial and Glucosidase Inhibitory ActivityChemistry select, Google scholar, -2019, accepted, 00
Rational design, molecular docking and synthesis of novel homopiperazinelinked imidazo[1,2a]pyrimidine derivatives as potent cytotoxic andantimicrobial agentsBioorganic & Medicinal Chemistry Letters, Scopus, -2019, 0, 00
Synthesis, Characterization and Antibacterial Activity of Some NovelC7Substituted2morpholinoN(pyridin2ylmethyl)quinazolin4amine DerivativesDer Pharma Chemica, , Others, -2018, 10, 40-48
Design, Synthesis and Biological Evaluation of 2(((5aryl1,2,4oxadiazol3yl)methyl)thio)benzo[d]oxazolesNew Antiinflammatory and Antioxidant AgentsChemistry select, Scopus, -2018, 3, 1-7
Focused library design and synthesis of 2mercapto benzothiazolelinked 1,2,4oxadiazoles as COX25LOX inhibitorsJournal of Molecular Structure , Scopus, -2018, 1159, 193-204
Synthesis and biological potentials of some new 1,3,4oxadiazoleanaloguesMedicinal chemistry research , Scopus, -2018, 27, 864-883
Stabilityindicating method ofentacaponerelated substances usingUPLC in finished dosage formCURRENT SCIENCE, Scopus, -2018, 114, 644
Synthesis, Biological Evaluation and Docking Studies of 1,3,4OxadiazoleFused Benzothiazole Derivatives for Anticancer DrugsLetters in Drug Design & Discovery, Scopus, -2018, 15, 199-1307
An approach towards the oxidation of 2amino4Hchromenes to 2imino2HchromenesTetrahedron Letters , Scopus, -2018, 59, 4616-4619
Molecular hybrid design, synthesis and biological evaluation of Nphenyl sulfonamide linked Nacyl hydrazone derivatives functioning as COX2 inhibitors new antiinflammatory, antioxidant and antibacterial agentsNEW JOURNAL OF CHEMISTRY, Scopus, -2017, 41, 13516-13532
New AntiInflammatory Hybrid NAcyl HydrazoneLinked Isoxazole Derivatives as COX2 InhibitorsRational Design, Synthesis and Biological Evaluation Chemistry selective, Scopus, -2017, 2, 8091-8100
A diversity oriented synthesis of natural product inspired molecular librariesOrganic & Biomolecular Chemistry, Scopus, -2017, 15, 9108-9120
Synthesis, molecular docking and in vitroantiproliferative activity of novel pyrano[3,2c]carbazole derivativesNew J. Chem.,, Scopus, -2016, 40, 8305--8315
DESIGNING NOVEL MEK1 INHIBITORS AS ANTICANCER AGENTSIJLP, Google scholar, -2016, 6, 22-33
Ionic liquidwater mixture promoted organictransformationsRSC Adv., , 5, , Scopus, -2015, 5, 51035-51054
Design, synthesis, and biological evaluation of quinazolinederivatives as aglucosidase inhibitorsMedicinal chemistry research , Scopus, -2015, 24, 2227-2237
Boronic acidcontaining CXCR12 antagonists optimization ofmetabolic stability, in vivo evaluation, and a proposed receptorbinding modelBMCL, Web of science, -2015, 25, 2280-2284
Design, synthesis and screening studies of potent thiazol2amine derivatives as fibroblast growth factor receptor 1 inhibitors. Current Topics in Medicinal Chemistry, Web of science, -2014, 14, 2031-2041
Pyrrolidine and piperidine based chiral spiro andfused scaffolds via buildcouplepair approach. RSC Adv, Scopus, -2014, 14, 10619-10626
A reagent based DOS strategy via Evans chiral auxiliaryhighly stereoselective Michael reaction towardsoptically active quinolizidinones, piperidinones andpyrrolidinones3RSC Adv., Scopus, -2013, 3, 2404-2411
Diversity Oriented Synthesis of Macrocyclic Diaryl Ethers by DtzBenzannulationAsian J. Org. Chem, Web of science, -2013, 2, 862-868
Synthesis of Privileged Scaffolds by Using DiversityOriented SynthesisChem. Asian J. 2013, 00, 0 0, Web of science, -2013, 0, 00
Fibroblast Growth Factor Receptor InhibitorsCurrent Pharmaceutical Design, Web of science, -2013, 19, 687-701
Development of glucosidase inhibitors by roomtemperature CC cross couplings of quinazolinonesOrg. Biomol. Chem, Scopus, -2013, 11, 4778-4791
ReagentBased DOS Developing a Diastereoselective Methodology toAccess Spirocyclic and Fused Heterocyclic Ring Systems**Chem. Asian J., Web of science, -2012, 7, 2351-2360
Molecular modeling of Bt Cry1Ac (DIDII)ASAL (Allium sativum lectin)fusionprotein and its interaction with aminopeptidase N (APN) receptor ofManduca sextaJournal of Molecular Graphics and Modelling , Scopus, -2012, 33, 61-67
Discovery and Preclinical Evaluation of a Novel Class of Cytotoxic Propynoic Acid Carbamoyl Methyl Amides (PACMAs)J. Med. Chem., Scopus, -2011, 54, 2902-2914
Virtual screening studies on HIV1 reverse transcriptase inhibitorsto design potent leadsEuropean Journal of Medicinal Chemistry, Scopus, -2011, 46, 851-859
A wideranging review on Nasicon type materialsJ Mater Sci, Scopus, -2011, 46, 2821-2837
A threedimensional pharmacophoremodelling of ITK inhibitors and virtualscreening for novel inhibitorsSAR and QSAR in Environmental Research, Scopus, -2011, 22, 171-190
Ligandbased and structurebased approaches in identifyingideal pharmacophore against cJun Nterminal kinase3J Mol Model, Scopus, -2011, 17, 151-163
Insilico studies on anthrax lethal factor inhibitors Pharmacophore modeling andvirtual screening approaches towards designing of novel inhibitors for a killerJournal of Molecular Graphics and Modelling , Scopus, -2010, 29 , 256-265
Three Dimensional Molecular Field Analysis of Thiomorpholine Analogs of TACE Inhibitors Using Receptor Based AlignmentLetters in Drug Design & Discovery, Web of science, -2010, 7 , 269-274
Combined pharmacophore and structureguided studies to identify diverseHSP90 inhibitorsJournal of Molecular Graphics and Modelling, Scopus, -2010, 28, 472-477
Modeling of human caspase5 protein and docking studies of caspase5 inhibitors against modeled caspase5Journal of Global Pharma Technology , Google scholar, -2010, 2, 1-5
Discovery of potential ZAP70 kinase inhibitors Pharmacophore design,database screening and docking studiesEuropean Journal of Medicinal Chemistry, Scopus, -2009, 44, 4793-4800
Knowledge basedidentification of MAOB selective inhibitors using pharmacophore and structure based virtual screening modelsEuropean Journal of Medicinal Chemistry, Scopus, -2009, 44, 3584-3590
Discovery of Novel SmallMolecule Inhibitors of Human Epidermal Growth Factor Receptor2Combined Ligand and TargetBased ApproachJ. Med. Chem. , Scopus, -2008, 51, 3367-3377
Discovery of 3acetyl4hydroxy2pyranone derivatives and theirdifluoridoborate complexes as a novel class of HIV1 integrase InhibitorsBioorganic & Medicinal Chemistry, Scopus, -2008, 16, 8988-8998
QSAR analysis of 1,3diaryl4,5,6,7tetrahydro2Hisoindolederivatives as selective COX2 inhibitorsEuropean Journal of Medicinal Chemistry , Scopus, -2008, 43, 1559-1569
Powder Xray diffraction, infrared and conductivity studiesof AgSbMP3O12 (M Al, Ga, Fe and Cr)Materials Research Bulletin , Scopus, -2008, 43, 1509-1518
Pharmacophore modeling and virtual screening studies to designsome potential histone deacetylase inhibitors as new leadsJournal of Molecular Graphics and Modelling , Scopus, -2008, 26, 935-946
HIV1 Integrase Inhibitors2005^2006 UpdateMedicinal Research Reviews, Scopus, -2008, 28, 118-154
Preparation, characterization and conductivity studiesof a Nasicon system Ag32xTaxAl2x (PO4)3.(a) 204, No. phys. stat. sol. , Web of science, -2007, 10, 3454-3462
Preparation, characterization, conductivity and thermalexpansion studies of Ca0.5SbMP3O12 (M Al, Fe, Cr)J Mater Sci, Web of science, -2007, 42, 3613-3620
Pharmacophore mapping of diverse classesof farnesyltransferase inhibitors. Bioorganic & Medicinal Chemistry Letters, Scopus, -2007, 17, 1594-1600
Preparation, characterization, and impedance studies of Li Sb M ( P O 4 ) 3 ( M Al , Fe,and Cr) JOURNAL OF APPLIED PHYSICS, Web of science, -2006, 100, 083707
Ligand Coordinate Analysis of SC558 from the Active Site to the Surface of COX2 AMolecular Dynamics Study. J. Chem. Inf. Model., Scopus, -2006, 46, 1784-1794
Synthesis, molecular docking, antiproliferative, and antimicrobialactivity of novel pyrano[3,2c]carbazole derivativesMed Chem Res, Scopus, -2006, 25, 2093-2103
A REVIEW ON ANTIHCV AGENTS TARGETING ACTIVE SITE AND ALLOSTERIC SITES OF NONSTRUCTURALPROTEIN 5B [NS5B]International Journal of Pharmacy and Pharmaceutical Sciences, Google scholar, -2006, 8, 1-18
Preparation, characterization and impedance study of AgTaMP3O12(MAl, Ga, In, Cr, Fe and Y)Solid State Ionics, Web of science, -2005, 176, 2701-2710
Virtual Screening of 4Anilinoquinazoline Analogues as EGFR Kinase InhibitorsImportance of Hydrogen Bonds in the Evaluation of Poses and Scoring FunctionsJ. Chem. Inf. Model, Web of science, -2005, 45, 725-738
Design of EGFR Kinase Inhibitors A LigandBased Approachand Its Confirmation with StructureBased StudiesBioorganic & Medicinal Chemistry , Scopus, -2003, 11, 4643-4653
Analogue Based Design of MMP13 (Collagenase3) Inhibitors. Bioorganic & Medicinal Chemistry Letters, Scopus, -2002, 12, 2689-2693
Title of the project | Funded by | Duration | Sanctioned date |
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NHeterocyclic CarbeneStabilized Silaallenes, Silacumulenes, Phosphaallenes and Phosphacumulenes. | DST | 36 | 26-Oct-2017 |
Traditional and New Approaches Towards the Discovery of Dengue Protease Inhibitors Potent and Druglike Antiviral Agents against Dengue Fever | SERB_DST | 36 | 04-Jun-2016 |
Title of the project | Funded by | Duration | Sanctioned date |
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Title of the book | Book / Chapter | Name of the publisher | Subject area | Edition | Page numbers | ISBN | Published year |
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ComputerAided Techniques in Design of HIV1 Integrase Inhibitors | Chapters | Wiley Series | Medicinal Chemistry | 10 | 389-413 | 9780470184745 | 2011 |
Board name | Journal name |
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Board name | Journal name |
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Wiley | Chemistry Select |
Elsevier | Journal Molecular Structure |
Seminar name | Organized by | Venue | Start date | End date | Title of the paper presented | Role | Co presenter |
---|---|---|---|---|---|---|---|
National | Nalanda college of pharmacy, Nalgonda | Nalgonda | 29-Mar-2019 | 29-Mar-2019 | Resource Person | ||
National | GITAM, Hyederabd | hyderabad | 06-Sep-2018 | 08-Sep-2018 | Organized | ||
National | GITAM | Hyderabad | 23-Oct-2017 | 23-Oct-2017 | Organized | ||
National | hyderabad | hyderabad | 14-Jul-2017 | 16-Jul-2017 | Resource Person | ||
National | Tara Govt. College ,Sangareddy | Tara Govt. College ,Sangareddy | 29-Dec-2016 | 30-Dec-2016 | Resource Person | ||
National | GITAM | GITAM, Hyderabad | 02-Apr-2016 | 02-Apr-2016 | Organized | ||
National | SKSD mahila college, Tanuku | Tanuku | 30-Jan-2016 | 31-Jan-2016 | Resource Person | ||
National | Tara Govt. College ,Sangareddy | Tara Govt. College ,Sangareddy | 08-Jan-2015 | 09-Jan-2015 | Resource Person |
Seminar name | Organized by | Venue | Start date | End date | Title of the paper presented | Role | Co presenter |
---|---|---|---|---|---|---|---|
International | MGU, KOTTAYAM, KERALA | KOTTAYAM, KERALA | 08-Dec-2017 | 10-Dec-2017 | Resource Person | ||
International | jnu | jnu,delhi | 07-Apr-2017 | 09-Apr-2017 | Resource Person | ||
International | jntuh | jntuh | 04-Oct-2016 | 06-Oct-2016 | Participated | ||
International | Schrodinger | IISc, Bengolore | 16-Sep-2013 | 17-Sep-2013 | Resource Person | ||
International | GITAM | GITAM, Vishakapatnam | 28-Jul-2011 | 29-Jul-2011 | Participated | ||
International | OMICS | Hyderabad | 21-Mar-2011 | 23-Mar-2011 | Resource Person |
Title of the thesis | Name of the student | Name of the college / university | Major subject area | Year of admission | Type of admission | Thesis specification |
---|---|---|---|---|---|---|
Rational Design, Synthesis of hetero cyclic compouds of anti cancer agents | Madhu Sudhana Reddy Gangireddy | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Novel Design, Synthesis of hetero cyclic compouds of anti cancer agents | Manohar Mantipally | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Design, Synthesis of hetero cyclic compouds of anti viral agents | Venkatnarayana chowdary Maddipati | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Design, Synthesis of hetero cyclic compouds of anti cancer agents | Gopal Muddasani | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Novel Design, Synthesis of hetero cyclic compouds of anti cancer agents | Kalisavali | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Design, Synthesis of hetero cyclic compouds of anti viral agents | Sidvilas | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Design, Synthesis of hetero cyclic compouds of anti cancer agents | Anil Kumar | GITAM | Medicinal Chemistry | 2015 | Part time | PhD |
Design, synthesis and insilco studies of BenzothiazoleBenzooxazole based hetrero cyclic agents as a COX2 inhibitors | Satyanarayan.Y | GITAM | Medicinal Chemistry | 2014 | Part time | PhD |
Identification, synthesis and biological evaluation of new Quinazoline and BINOL based Antidiabetic and Antibacterial agents | Ashok Reddy.A | GITAM | Medicinal Chemistry | 2014 | Part time | PhD |
Title of the thesis | Name of the student | Name of the college / university | Major subject area | Year of admission | Type of admission | Thesis specification |
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DEVELOPMENT AND VALIDATION OF NOVEL STABILITY INDICATING METHODS FOR SELECTED DRUGS OF CANCER AND PARKINSON DISEASES USING RPHPLC AND UPLC TECHNIQUES | Naresh Konduru | GITAM | Analytical Chemistry | 2018 | Part time | PhD |
Title of the thesis | Name of the student | Name of the college / university | Major subject area | Year of admission | Type of admission | Thesis specification |
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Name of the award | Awarded by | Awarded year |
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Best Researcher | GITAM | 2017 |
Best Employee | GVKBIO | 2012 |
Organization name | Membership category | Membership type |
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Indian Science Congress Association | Life | Member |
Title | Application number | Category | Submitted date |
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Title | Application number | Category | Submitted date |
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Title | Application number | Category | Submitted date |
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Pesticidal Compositions And Processes Related Thereto | US 9,615,576 B2 | US | 17 Feb, 2017 |
Pesticidal Compositions And Processes Related Thereto | US 20140206537A1 | US | 25 Mar, 2014 |
Pesticidal Compositions And Processes Related Thereto | US 9,615,576 B2 | US | 21 Jun, 2012 |