Jagattaran Das
Professor, GSP, VSP
Prof. Jagattaran Das is an accomplished medicinal chemist with 25+ years of experience in academia and industry. He earned his Ph.D. in Chemistry from the Indian Institute of Science, Bangalore, followed by postdoctoral training in France, Germany, and Japan. He spent nearly 20 years in the areas of drug discovery before transitioning to academia. His expertise lies in synthesizing small molecule NCEs, focusing on the treatment of infectious diseases and metabolic as well as CNS disorders.
Research Publications
- 1. A glimpse into green chemistry practices in the pharmaceutical industry S. Sharma, J. Das, W. Braje, A. Dash, S. Handa, ChmSusChem., 2020, 13, 2859-2875
- 2. Convenienet synthesis of nucleosides of 2-deoxy-2-nitro-D-galactose and N-acetyl-D-galactosamine G. A. Winterfeld, J. Das, R. R. Schmidt, Eur. J. Org. Chem., 2000, 3047-3050.
- 3. Catalytic enantioselective meso-epoxide ring opening reaction with phenolic oxygen nucleophile promoted by gallium heterobimetallic multifunctional complexes S. Matsunaga, J. Das, J. Roels, E. M. Vogl, N, Yamamoto, T. Iida, K. Yamaguchi, M. Shibasaki, J. Am. Chem. Soc., 2000, 122, 2252-2260.
- 4. Direct catalytic asymmetric aldol reaction N. Yoshikawa, Y. M. A. Yamada, J. Das, H. Sasai, M. Shibasaki, J. Am. Chem. Soc., 1999, 121, 4168- 4178.
- 5. Convenient glycoside synthesis of amino sugars: Michael-type addition to 2-nitro-D-galactal J. Das, R. R. Schmidt, Eur. J, Org. Chem., 1998, 1609-1613.
Ongoing Research Projects
- a) Synthesis of bicyclic amino-sugars and nucleosides, b) Synthesis and evaluation of new anti-bacterials.
Authored Books
- Nil
Expertise
- Design, synthesis, and SAR studies of molecules having medicinal application
- Synthesis of small molecules as NCE (New Chemical Entities) in the areas of anti-infective particularly in anti-microbial resistance; metabolic & CNS disorders
- Expertise in establishing research infrastructure, people management, and business strategy development
- Working knowledge in clinical development of NCEs
- Establishing industry-academic partnerships