Yerra Veera Ganesh

Assistant Professor

Department of Pharmacology

GITAM School of Pharmacy

Visakhapatnam

Education

Ph. D.

vyerra@gitam.edu

Social Media

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ORCiD

Dr. Veera Ganesh Yerra is a dedicated pharmacologist interested in elucidating novel inflammatory and metabolic mechanisms underlying cardiac diseases. With a comprehensive educational background in Pharmacology and Toxicology, Dr. Ganesh has cultivated extensive expertise in basic and translational research methodologies, aiming to contribute significantly to advancing cardiovascular therapeutics. Dr. Ganesh's research is widely recognized, evidenced by his substantial publications and awards.

Research Publications

Yerra VG, Batchu SN, Kaur H, Kabir G, Liu Y, Advani SL., Sadeghian S, Sedrak P, Billia F, Kuzmanov U, Gramolini AO, Connelly KA, Advani A. Induction of interferon-stimulated gene 15 (ISG15) by pressure overload facilitates adverse ventricular remodelling. J Clin Invest. 2023 May 1133(9):e161453. doi: 10.1172/JCI161453. PMID: 37115698.
Yerra VG, Batchu SN, Kabir G, Advani SL, Liu Y, Siddiqi FS, Connelly KA, Advani A. Empagliflozin Disrupts a Tnfrsf12a-Mediated Feed Forward Loop That Promotes Left Ventricular Hypertrophy. Cardiovasc Drugs Ther. 2022 Aug36(4):619-632. PMID: 33886003.
Batchu SN, Kaur H, Yerra VG*, Advani SL, Kabir MG, Liu Y, Klein T, Advani A. Lung and Kidney ACE2 and TMPRSS2 in Renin-Angiotensin System Blocker-Treated Comorbid Diabetic Mice Mimicking Host Factors That Have Been Linked to Severe COVID-19. Diabetes. 2021 Mar70(3):759-771. PMID: 33310740. (*Equal first author)
Yerra VG, Kalvala AK, Sherkhane B, Areti A, Kumar A. Adenosine monophosphate-activated protein kinase modulation by berberine attenuates mitochondrial deficits and redox imbalance in experimental diabetic neuropathy. Neuropharmacology. 2018 Mar 15131:256-270. PMID: 29273519.
Yerra VG, Kalvala AK, Kumar A. Isoliquiritigenin reduces oxidative damage and alleviates mitochondrial impairment by SIRT1 activation in experimental diabetic neuropathy. J Nutr Biochem. 2017 Sep47:41-52. PMID: 28528294.

Expertise

In vivo and in vitro screening of small molecule modulators
Discovery and pre-clinical validation of novel molecular targets for inflammatory and cardiac diseases
Elucidation of molecular pathomechanisms of cardiometabolic diseases