Soniya Rani

Assistant Professor

Department of Pharmacology

GITAM School of Pharmacy

Hyderabad

Education

Ph. D.

srani@gitam.edu

Social Media

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ORCiD

Dr. Soniya Rani, Assistant Professor in Pharmacology at GITAM School of Pharmacy, holds a Ph.D. in Pharmaceutical Sciences and a Gold Medalist in M.Pharm from Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow. Her research focuses on cancer biology, COPD, and hypoxia regulation. She has published high-impact publications, holds patents, received ICMR-SRF, and presented papers at national and international conferences.

Research Publications

1. Soniya Rani, Trivedi R, Ansari MN, Saeedan AS, Kumar D, Singh SK, Mukherjee A, Singh M, Kaithwas G. A novel quinazoline derivative exhibits potent anticancer cytotoxicity via apoptosis and inhibition of angiogenesis in DMBA-induced mammary gland carcinoma. Journal of Biochemical and Molecular Toxicology. 2024 Nov38(11):e70016, 1-18. doi: https://doi.org/10.1002/jbt.70016 2. Soniya Rani, Gautam, Swetlana, Sara A. Aldossary, Abdulaziz S. Saeedan, Mohd Nazam Ansari, and Gaurav Kaithwas. Effects of phenidone (DuCLOX-2/5 inhibitor) against N-methyl-N-nitrosourea induced mammary gland carcinoma in albino rats. Toxicology and Applied Pharmacology. 351 (2018): 57-63. doi: https://doi.org/10.1016/j.taap.2018.04.019 3. Soniya Rani, Subhadeep Roy, Manjari Singh, and Gaurav Kaithwas. Regulation of transactivation at C-TAD domain of HIF-1α by factor-inhibiting HIF-1α (FIH-1): A potential target for therapeutic intervention in cancer. Oxidative Medicine and Cellular Longevity. May 10 (2022): 1-21. doi: https://doi.org/10.1155/2022/2407223 4. Singh, Samipta, Priyanka Maurya, Soniya Rani, Nidhi Mishra, Raquibun Nisha, Priya Singh, and Shubhini A. Saraf. Development of doxorubicin hydrochloride–loaded whey protein nanoparticles and its surface modification with N-acetyl cysteine for triple-negative breast cancer. Drug Delivery and Translational Research. 12, no. 12 (2022): 3047-3062. doi: https://doi.org/10.1007/s13346-022-01169-8 5. Sonkar AB, Verma A, Yadav S, Kumar R, Singh J, Keshari AK, Rani Soniya, Kumar A, Kumar D, Shrivastava NK, Rastogi S. Antiproliferative effect of indeno [1, 2-d] thiazolo [3, 2-a] pyrimidine analogues on IL-6 mediated STAT3 and role of the apoptotic pathway in albino Wistar rats of ethyl carbamate-induced lung carcinoma: in silico, in vitro, and in vivo study. Cancer Cell International. 2024 Jun 2624(1):219. Cancer Cell International. doi: https://doi.org/10.1186/s12935-024-03390-6

Ongoing Research Projects

Synergistic Anticancer Strategy Using p(NAG‑co‑Acrylamide) loaded Nanocarriers for Dual Inhibition of Arachidonic‑Acid and Heparanase Pathways (GITAM Seed Grant)

Expertise

Hypoxia Regulation Cell Biology Cancer Animal Model Inflammatory Diseases Oxidative Stress