Dr. Krishna Karteek Chinchili is an established and enthusiastic medicinal chemistry research professional with 3+ years of experience in academia and industry. He recently completed his postdoctoral studies in the United States in the area of drug discovery and medicinal chemistry. His expertise lies in the area of Synthetic organic and medicinal chemistry, SAR studies of different NCEs, Molecular modelling studies, and biological evaluation of novel small molecules.
Research Publications
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Krishna kartheek. Chinchilli, Andrea Angeli, Pavitra S Thacker, Laxman naik. K, Rashmita Biswas, Mohammed Arifuddin, and Claudiu T. Supuran, Design Synthesis, and Biological Evaluation of 1,2,3 - Triazole-linked triazino[5,6-b] indole- benzene sulfonamide Conjugates as Potent Carbonic Anhydrase I, II, IX and XIII inhibitors, Metabolites 2020,10, 200; doi:10.3390/metabo10050200, Impact factor: 5.581
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Krishna Kartheek Chinchilli, Venkata Nagamani Royyala, Pavitra S. Thacker, Andrea Angeli, Srikanth Danaboina, Priti Singh, Srinivas Nanduri, Claudiu T. Supuran, Mohammed Arifuddin, Design, synthesis, SAR and biological evaluation of Saccharin based hybrids as potent Carbonic anhydrase inhibitors, Arch. Pharm. 2022; e2200019, doi: 10.1002/ardp.202200019, Impact factor: 3.751
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Krishna Kartheek Chinchilli, Priti Singh, Baijayantimala Swain, Nerella Sridhar Goud, Dilep Kumar Sigalapalli, Abhishek Choli , Andrea Angeli, Srinivas Nanduri, Venkata Madhavi Yaddanapudi, Claudiu T. Supuran and Mohammed Arifuddin, Development of novel Indole-3-Sulfonamide-heteroaryl hybrids as Carbonic anhydrase inhibitors: Design, synthesis and invitro-screening, Anti-cancer agents and Medicinal chemistry doi: 10.2174/1871520623666230227092821, Impact factor: 2.505
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Krishna Kartheek Chinchilli, Ravikumar Akunuri, Ramulu Parupalli, Andrea Angeli, Shaik Mahammed Ghouse, Mohammed Arifuddin, Venkata Madhavi Yaddanapudi, Claudiu T. Supur an, Nanduri Srinivas Design, synthesis and structure activity studies of new rhodanine derivatives as carbonic anhydrase II and IX inhibitors. Arch. Pharm. doi: 10.1002/ardp.202300205, Impact factor: 3.751
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Pavitra S. Thacker, Danaboina Srikanth, Dr. Andrea Angeli, Priti Singh, Krishna Kartheek Chinchilli, Dr. Mohammed Arifuddin, Prof. Claudiu T. Supuran, Coumarin‐Thiourea Hybrids Show Potent Carbonic Anhydrase IX and XIII Inhibitors. Chemmedchem2021, 16, 1252-1256, doi.org/10.1002/cmdc.202000915. Impact factor: 3.12
Expertise
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Synthetic organic and Medicinal chemistry, Molecular modelling studies, Structural activity relationship studies, Carbonic anhydrase Inhibition, Handling NMR Bruker Instrument, LC-MS for structural evaluation